tirzepatide (Ly3298176) ye glucose bbiri-esinziira ku insulinotropic polypeptide (GIP) ne glucagon-nga peptide-1 .
Ssukaali ow’ekika eky’okubiri: tirzepatide ekozesebwa nga ekwatagana n’emmere n’okukola dduyiro okuyamba okulongoosa okufuga ssukaali mu musaayi mu bantu abakulu abalina ssukaali ow’ekika eky’okubiri.Okuddukanya obuzito obutasalako: Era kikozesebwa okuyamba mu kugejja n’okulabirira omugejjo mu bantu abakulu abalina omugejjo oba abo abagejjulukuka nga waakiri omugejjo gumu{{3}Stulooka, gamba nga puleesa ey’ekika kya 2, omugejjo omungi, oba omugejjo omungi, oba obststles, sleester, sukaali omungi.
Obulung’amu bwa tirzepatide mu kuziyiza obuzito obutawona (okukendeeza ku buzito n’okulabirira) nga bigattiddwa wamu n’emmere ekendeezeddwa-Kalorie n’okweyongera kw’emirimu gy’omubiri kwateekebwawo placebo-okugezesebwa okufugibwa kw’abantu abakulu abalina omugejjo oba omugejjo nga waakiri obuzito bumu-embeera ekwatagana.
Okunoonyereza kuno kwapima okukendeera kw’obuzito oluvannyuma lwa wiiki 72 mu bantu 2,519 abaali bafunye oba 5 mg, 10 mg, oba 15 mg za tirzepatide omulundi gumu buli wiiki n’abantu 958 abaafunye empiso za placebo buli wiiki. Mu kugezesebwa kwombi, oluvannyuma lwa wiiki 72 ez’obujjanjabi, abeetabye mu kugezesebwa abaafunye tirzepatide ku mitendera gyonna esatu egya dose baafuna okukendeera okw’amaanyi mu bibalo mu buzito bw’omubiri bw’ogeraageranya n’abo abaafunye placebo, n’ebitundu ebinene eby’abeetabye mu kugezesebwa abaafunye tirzepatide batuuse waakiri 5% okukendeera kw’obuzito bw’ogeraageranya n’eddagala eriweweeza
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